Dr. Inbal Abutbul Ionita received her PhD from the Faculty of Biotechnology and Food Engineering at the Technion, under the supervision of Prof. Dganit Danino. Her main interests are: Structure-function relations of membrane proteins, Membrane fusion and fission and Viral membrane fusion.
Publications:
Solid lipid nanoparticles and nanoemulsions with solid shell: Physical and thermal stability
Koroleva M, Portnaya I, Mischenko E, Abutbul-Ionita I, Kolik-Shmuel L, Danino D. Journal of Colloid and Interface Science 610, 61–69 (2022)
Engineering pH‐Sensitive Stable Nanovesicles for Delivery of MicroRNA Therapeutics
Boloix A, Feiner-Gracia N, Köber M, Repetto J, Pascarella R, Soriano A, Masanas M, Segovia N, Vargas-Nadal G, Danino D, Abutbul-Ionita I, Foradada L, Roma J, Sánchez de Toledo J, Gallego S, Veciana J, Albertazzi L, Segura MF, Ventosa N. Small, 2101959 (2021)
Order from disorder with intrinsically disordered peptide amphiphiles
Jacoby G, Asher M.S, Ehm T, Abutbul-Ionita I, Shinar H, Azoulay-Ginsburg S, Zemach I, Koren G, Danino D, Kozlov M.M, Amir R.J, and Beck R. Journal of the American Chemical Society 143, 11879-11888 (2021)
Lipid Nanoparticle RBD-hFc mRNA Vaccine Protects hACE2 Transgenic Mice against a Lethal SARS-CoV-2 Infection
Elia U, Rotem S, Bar-Haim E, Ramishetti S, Naidu G.S, Gur D, Aftalion M, Israeli M, Bercovich-Kinori A, Alcalay R, Makdasi E, Chitlaru T, Rosenfeld R, Israely T, Melamed S, Abutbul Ionita I, Danino D, Peer D, and Cohen O. Nano Lett 21 (11), 4774–4779 (2021)
Impact of Chemical Composition on the Nanostructure and Biological Activity of α-Galactosidase-Loaded Nanovesicles for Fabry Disease Treatment
Tomsen-Melero J, Passemard S, García-Aranda N, Díaz-Riascos Z.V, Gonzalez-Rioja R, Pedersen J.N, Lyngsø J, Merlo-Mas J, Cristóbal-Lecina E, Corchero J.L, Pulido D, Camara-Sa ́ nchez P, Portnaya I, Ionita I, Schwartz S, Jr., Veciana J, Sala S, Royo M, Córdoba A, Danino D, Pedersen J.S, Gonzalez-Mira E. ACS Applied Materials & Interfaces 13 (7), 7825-7838 (2021)
Multidomain drug delivery systems of β-casein micelles for the local oral co-administration of antiretroviral combinations
Chauhan P.S, Abutbul Ionita I, Halamish H.M, Sosnik A, Danino D.Journal of Colloid and Interface Science 592, 156-166 (2021)
Ferritin is secreted via 2 distinct nonclassical vesicular pathways
Truman-Rosentsvit, M., Berenbaum, D., Spektor, L., Cohen, L.A., Belizowsky-Moshe, S., Lifshitz, L., Ma, J., Li, W., Kesselman, E., Abutbul-Ionita, I., Danino, D., Gutierrez, L., Li, H., Li, K., Lou, H., Regoni, M., Poli, M., Glaser, F., Rouault, T.A. and Meyron-Holtz, E.G. Blood, 131(3):342-352 (2018)
Structure and characterisation of hydroxyethylcellulose–silica nanoparticles
Mansfield, E.D.H., Pandya, Y., Mun, E.A., Rogers, S.E., Abutbul-Ionita, I., Danino, D., Williams, A.C. and Khutoryanskiy, V.V. RSC Adv, 8(12):6471-6478 (2018)
Amphiphilic Nanoparticle-in-Nanoparticle Drug Delivery Systems Exhibiting Crosslinked Inorganic Rate-Controlling Domains
Talal, J., Abutbul-Ionita, I., Schlachet, I., Danino, D., and Sosnik, A.
Chemistry of Materials, (2016)
Poly(glycoamidoamine) Brushes Formulated Nanomaterials for Systemic siRNA and mRNA Delivery in Vivo. Dong, Y., Dorkin, J., Wang, W., Chang, P., Webber, M., Tang, B., Abutbul-Ionita, I., Danino, D., DeRosa, F., Heartlein, M., Langer, R. & Anderson, D. (2016). Nano Lett, 16(2), 842-848.
Effect of temperature and loading on the structure of beta-casein/ibuprofen assemblies. Turovsky, T., Portnaya, I., Kesselman, E., Ionita-Abutbul, I., Dan, N., & Danino, D.(2015). J Colloid Interface Sci, 449, 514-521.
Membrane tethering and nucleotide-dependent conformational changes drive mitochondrial genome maintenance (Mgm1) protein-mediated membrane fusion
Abutbul-Ionita, I., Rujiviphat, J., Nir, I., McQuibban, G. A. and Danino, D.
J Biol Chem, 287(44), 36634-36638 (2012)
Stalk domain of the dynamin-like MxA GTPase protein mediates membrane binding and liposome tubulation via the unstructured L4 loop. von der Malsburg, A., Abutbul-Ionita, I., Haller, O., Kochs, G., & Danino, D. (2011). J Biol Chem, 286(43), 37858-37865.
Conserved eukaryotic fusogens can fuse viral envelopes to cells. Avinoam, O., Fridman, K., Valansi, C., Abutbul, I., Zeev-Ben-Mordehai, T., Maurer, U. E., Danino D, Grünewald, K., White, J. M. ,& Podbilewicz, B. (2011). Science, 332(6029), 589-592.
Self-Assembly of a Modified Amyloid Peptide Fragment: pH-Responsiveness and Nematic Phase Formation. Hamley, I. W., Castelletto, V., Moulton, C., Myatt, D., Siligardi, G., Oliveira, C. L. P., Pedersen, J.S., Abutbul, I., & Danino D. (2010). Macromol Biosci, 10(1), 40-48.